At the ASPIRE Lab, our research is organized around three interconnected pillars that together aim to transform how organ failure is understood, supported, and treated. We integrate systems-level physiology, advanced engineering, and computational modeling to develop mechanistically grounded and data-driven approaches that improve patient outcomes.

Rather than separating discovery, technology development, and data science, we unify them. Experimental platforms inform device innovation. Clinical data refine computational models. Engineering solutions are evaluated within physiologic frameworks. Across all efforts, our focus remains constant: to define the physiologic state of failing organs and design technologies and strategies that restore function safely and effectively.